The present invention relates to a biofilter fence for preventing the dispersion of odor and dust. More specifically, the invention is installed corresponding to a ventilation means that discharges indoor air from a pig house, such that the discharged air is retained for a certain period of time inside a fence member and then released to the outside after passing through the fence member. Each of the upper, lower, left/right, and rear surfaces of the fence member is formed in multiple layers of biofilters having different materials and flow resistances, so that dust and odor can be efficiently removed.